Prolozone Injections
Non-Surgical Injections for Joint, Muscle & Spinal Pain
At Leigh Injection Clinic, we offer Prolozone therapy and prolotherapy for patients exploring non-surgical injection options for musculoskeletal and spinal conditions.
Prolozone combines prolotherapy techniques with medical ozone. Our clinicians provide targeted injection procedures for selected joint, tendon, ligament and spinal presentations, with treatment tailored to each patient.
What Is Prolozone Therapy?
Prolozone is an injection treatment that combines prolotherapy solutions with medical ozone, an oxygen-ozone gas mixture.
The procedure involves injections into selected joints, ligaments, tendons and surrounding musculoskeletal tissues. Prolozone is also offered at our clinic for selected spinal presentations.
Each treatment plan is based on your symptoms, clinical examination and individual needs.
How Does Prolozone Therapy Work?
Prolozone combines two injection techniques:
Prolotherapy: Involves injecting a solution, commonly dextrose-based, into targeted musculoskeletal tissues.
Medical Ozone: An oxygen-ozone gas mixture administered to the selected treatment area.
These components form the Prolozone procedure, with the injection technique and treatment schedule tailored to the area being treated.
Musculoskeletal & Spinal Conditions We Assess
We provide consultations for patients experiencing:
Osteoarthritis and joint pain
Knee, hip and shoulder pain
Tendon and ligament problems
Bursitis
Sports-related injuries
Foot and ankle pain
Elbow, wrist and hand pain
Lower back and neck pain
Sciatica and disc-related symptoms
Sacroiliac joint pain
Your clinician will assess your condition and discuss the available injection options, including whether Prolozone is suitable for you.
Prolozone for Joint, Tendon & Ligament Problems
Our musculoskeletal injection service includes Prolozone consultations for patients with joint pain, tendon complaints, ligament problems and sports-related injuries.
Following a clinical examination and review of any relevant imaging, your clinician will explain the proposed injection sites, procedure and treatment plan.
Prolozone for Back Pain & Spinal Conditions
We also provide Prolozone consultations for patients with lower back pain, neck pain, sciatica, disc-related symptoms and sacroiliac joint complaints.
Our clinicians assess your symptoms and examination findings before discussing suitable injection options.
We do not perform spinal corticosteroid injections.
What Happens During Prolozone Treatment?
1. Consultation & Assessment
We review your symptoms, medical history, relevant imaging and treatment goals, followed by a physical examination.
2. Personalised Treatment Plan
Your clinician explains the proposed injection procedure, treatment areas, number of sessions and aftercare.
3. Targeted Injections
The prolotherapy solution and medical ozone are administered to the selected musculoskeletal or spinal treatment area using the appropriate technique.
4. Aftercare & Follow-Up
You receive clear aftercare advice, with progress reviewed and further appointments arranged where appropriate.
Prolozone vs Prolotherapy
Both approaches involve targeted injections, but differ in their composition.
Prolotherapy typically involves a dextrose-based solution injected into selected musculoskeletal tissues.
Prolozone therapy incorporates medical ozone alongside prolotherapy principles.
Our clinicians will explain the differences and discuss the options appropriate for your circumstances.
Reviews
Reduce your symptoms. Move pain-free. Let our team of experts guide you back to health.
PERSONALISED INJECTION THERAPY
Frequently Asked Questions
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Prolozone® is a regenerative injection therapy that supports tissue repair and reduces pain by delivering a mixture of oxygen–ozone gas and therapeutic nutrients into the affected area. It enhances the body’s ability to heal naturally by improving circulation and restoring cellular energy.
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Prolozone is particularly effective for:
Back pain, neck pain & sciatica
Degenerative joint disease & arthritis
Hip, knee & shoulder pain
Tendon, ligament & soft-tissue injuries
Sporting injuries
Plantar fasciitis & chronic inflammation
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Yes, Prolozone is a leading non-surgical treatment option for spinal pain conditions. Steroid injections are not performed in the spine at our clinic; Prolozone is used instead because it encourages repair rather than simply reducing inflammation.
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No, this treatment is performed without ultrasound. Target tissues for Prolozone are ligament and attachment sites that are best accessed using anatomical accuracy and manual technique.
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Prolozone supports the repair process by:
Boosting oxygen levels in damaged tissue
Improving mitochondrial energy production
Reducing inflammation and pain
Activating natural tissue regeneration
This results in more durable healing than conventional pain-relief techniques.
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Most patients require a course of 3–6 treatments, depending on severity and response. Improvements often begin after the first or second session.
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Patients frequently experience:
Significant pain reduction
Greater range of movement
Better joint strength and stability
Long-term improvement in mobility
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Yes, Prolozone is generally very safe, with minimal short-term side effects such as temporary stiffness or mild discomfort.
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Cortisone suppresses inflammation temporarily - Prolozone supports the repair of the cause of pain. Cortisone can weaken tissues over time, whereas Prolozone strengthens them.
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Ideal candidates include those with:
Persistent pain not responding to traditional care
Joint degeneration, osteoarthritis or instability
Soft tissue injuries, sprains or repetitive strain
A desire to avoid steroids, surgery or long-term medication

